It's sort of funny seeing Cartman as a socially successful "restauranteur" with a secret formula for his Carman-burgers.
The script takes the interesting position that people with Asperger's see the world exactly as it is, and that "normal" people can't function if they're forced to deal with "the whole truth." (Is Cartman a "Rosenfelfs feminine" in the "polarity theory"?; a burger manager probably wouldn't be). Then there are squads of "extraterrestrial aliens" going around managing the truth (an allusion to Facebook?)